Melanotan II
A cyclic lactam analogue of alpha-melanocyte-stimulating hormone (α-MSH). Melanotan II is a non-selective melanocortin receptor agonist studied for its effects on pigmentation, energy homeostasis, and reproductive biology. A foundational compound in melanocortin receptor pharmacology research.
Research Use Only. Melanotan II is sold exclusively for in vitro research and laboratory use by qualified scientists. Not for human consumption, veterinary use, or clinical administration.
Research Literature
Published Research
Melanotan II is a foundational non-selective melanocortin receptor agonist essential for studying pigmentation biology, energy homeostasis, and reproductive endocrinology.
Melanotan II structure-activity and receptor pharmacology
Key finding: Established structure-activity relationships for cyclic alpha-MSH analogues across all five melanocortin receptor subtypes.
PubMed 9735944 ↗Central melanocortin system and energy regulation
Key finding: MC4R activation by Melanotan II suppresses food intake and increases energy expenditure via hypothalamic circuits.
PubMed 11266465 ↗Pigmentation research with Melanotan II
Key finding: Dose-dependent melanogenesis activation confirms utility as pharmacological tool for melanocortin pathway research.
PubMed 12810694 ↗Same Category