Epithalon (Epitalon)
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) and analogue of the natural pineal gland peptide Epithalamin. Research has focused on its effects on telomerase activation, telomere elongation, circadian rhythm regulation, and neuroendocrine axis modulation. A subject of significant longevity research.
Research Use Only. Epithalon (Epitalon) is sold exclusively for in vitro research and laboratory use by qualified scientists. Not for human consumption, veterinary use, or clinical administration.
Research Literature
Published Research
Epithalon is a synthetic pineal tetrapeptide studied for telomerase activation, telomere elongation, and circadian rhythm modulation in longevity research.
Epithalon peptide increases telomerase activity
Key finding: First demonstration that Epithalon activates telomerase and elongates telomeres in human somatic cells.
PubMed 12851467 ↗Melatonin and pineal peptides in circadian regulation
Key finding: Epithalon restores disrupted melatonin synthesis and normalizes circadian rhythm patterns in aged animals.
PubMed 14509234 ↗Epithalon and neuroendocrine aging
Key finding: Long-term Epithalon treatment reduced biomarkers of neuroendocrine aging and extended mean lifespan in rodent studies.
PubMed 16191830 ↗